Anything is possible:-)
That said, pranayama is a control of the breath with several different “benefits”. This you should actually feel in your own living since you are doing some pranayama that has one effect on the CNS and two others that have the opposite effect.
Since the movement of prana in the body is directed into nadis (energy channels) it is critical the physical body have alignment first. This is especially true when the pranayama being done is fiery, active, aggressive. When the body lacks this alignment the prana is not moved into the channels but rather into the organic body and that can cause serious issues.
As far as “prana is everything” it is germane to note that while that is old yoga it is not necessary a static state. Yoga, as a system has a flexibility (stages referred to as yugas) and should one read Sri Aurobindo (for example) one would note his transformation through yoga centers around light (photonic energy) not prana at all.
Physical well being is relevant because the body is the vessel that contains the spirit. Physical well being therefore is a requirement not an end.
There are very few “musts” in yoga. If what you are doing is working to move you toward light, evolve you, then it is perfect for you and not intellectualizing is required for your personal path.